Urinary microbiome associated with chronic allograft dysfunction in kidney transplant recipients
نویسندگان
چکیده
منابع مشابه
Increase of Th17 Cell Phenotype in Kidney Transplant Recipients with Chronic Allograft Dysfunction
This study was performed to determine the association of Th17 cell phenotype with chronic allograft dysfunction in kidney transplant recipients (KTRs). We compared the expression of Th17 cell phenotype in KTRs with chronic allograft dysfunction group (CAD, n = 52) with four control groups (long-term stable KTRs (LTS, n = 67), early stable KTRs (ES, n = 28), end stage renal disease (ESRD, n = 45...
متن کاملRisk factors of long-term graft loss in renal transplant recipients with chronic allograft dysfunction.
OBJECTIVES Graft loss owing to chronic allograft dysfunction is a major concern in renal transplant recipients. We assessed the affect of immune and nonimmune risk factors on death-censored graft loss in renal transplant recipients with chronic allograft dysfunction. MATERIALS AND METHODS We performed a retrospective, single-center study on 214 renal transplant recipients with chronic allogra...
متن کاملConversion of ciclosporin A to tacrolimus in kidney transplant recipients with chronic allograft nephropathy.
BACKGROUND Tacrolimus and ciclosporin might have different effects on intra-renal fibrosis and allograft function in chronic allograft nephropathy (CAN). It is difficult to predict the response to calcineurin inhibitor minimization in patients with CAN. METHODS This prospective randomized study compared ciclosporin A (CsA)-to-tacrolimus conversion (group A, target tacrolimus trough level 6-8 ...
متن کاملGenetic polymorphisms of Interleukin-18 are not associated with allograft function in kidney transplant recipients
Interleukin 18 (IL-18) is a proinflammatory cytokine that plays a role in host defense by upregulating both innate and acquired immune responses. Analysis of IL18 polymorphisms may be clinically important since their roles have been recognized in a variety of inflammatory and autoimmune disorders. However, the role of this cytokine polymorphisms in kidney transplant still remains unclear. In th...
متن کاملUrinary biomarkers in acute kidney transplant dysfunction.
BACKGROUND Acute kidney injury (AKI) is a common medical problem among kidney transplant recipients, which may cause a significant impact on patient and allograft survival. Currently, an allograft biopsy remains the 'gold standard' for assessing the cause of impaired kidney function. Limitations of the allograft biopsy include the risk of bleeding, injury to the adjacent viscera, and the possib...
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ژورنال
عنوان ژورنال: Clinical Transplantation
سال: 2018
ISSN: 0902-0063
DOI: 10.1111/ctr.13436